My mother was diagnosed with triple negative breast cancer at the age of 30, both of which are strong indicators of a genetic mutation. My mother was quick to expose my sisters and me to the danger we may face in young adulthood following her diagnosis.

Today, I want to dive into the role genomics has played in my journey. As an MD specialized in genomics, this journey has been an eye-opener regarding the clinical implementation of genomics and the accessibility of genomic profiling for real patients in British Columbia, Canada, and beyond. There have been good surprises and also situations where I've directly faced barriers and limitations surrounding the clinical use and implementation of genomics.

Treatment can be difficult for this type of breast cancer. Without receptors, triple negative tumors do not have the proteins they need to respond to common breast cancer treatments like hormone and targeted therapy, which are used for hormone-positive or HER2-positive breast cancer. Research shows that some people have a greater chance of developing triple-negative breast cancer (TNBC) if they are subject to certain risk factors. 

Before it was known that genes could be linked to various cancers, 1970s research focused largely on viruses and their role in the development of cancer. With the knowledge that family history had an impact on cancer risk, Mary-Claire King, an American geneticist, began to theorize possibilities beyond viruses and started her mission in identifying the cause of breast cancer running in families.

In today’s post, we provide the questions that were sent in and asked during the live session of our Questions and Experts session held in June 2022. In this session, Rachel Mador-House, a certified Genetic Counsellor, answered questions about genetics and genetic testing. In the parentheses, you’ll find the timestamp of where to find the question in the on-demand video.

The risk of a COVID-19 diagnosis for breast cancer patients is still not completely known. Studies have come that show that cancer patients are more at risk of adverse effects if they develop COVID-19. However, a few studies state that compared to other cancer patients, breast cancer patients are at a lower risk of serious illness. The stage of breast cancer also seems to play a role in one’s risk level.

Dealing with breast cancer is challenging at the best of times, but in this time of uncertainty and when our health care system is having to quickly adapt to the impact of COVID-19, cancer patients are facing increased challenges and changes to treatment schedules and doctors’ appointments. This can bring additional anxiety and questions around how these changes will impact the success of treatments.

By now we've all heard the tips for how to stay safe during the COVID-19 pandemic: wash your hands, stay at home and practice social distancing. However, what might not be as widely shared and known is why and how these health tips help. While protecting yourself, your family and your community is important, equally important is understanding why you are being told to do certain things and how they help. Therefore, we’ve decided to explore the benefits and reasoning behind the two most repeated and shared mantras amidst the COVID-19 crisis.

In October 2013, Allegra Kawa of Edmonton had surgery to remove both her breasts.  She’s also considering surgery to remove her ovaries and uterus.