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Clinical Trials in Canada: What’s currently being offered in breast cancer? - Metastatic

Title of Study: A Phase 3b study to assess the safety and efficacy of RIBOCICLIB in combination with LETROZOLE for the treatment of men and pre/postmenopausal women with hormone receptor-positive, HER2-negative advanced breast cancer with no prior hormonal therapy for advanced disease

Patient Population: HR+ and HER2- locally advanced or metastatic breast cancer

Locations: Edmonton, Calgary, Vancouver, Halifax, Hamilton, Montreal, Regina, Saskatoon

Click HERE for more information.


Title of Study: A randomized, double-blind, Phase 3 study of PEMBROLIZUMAB + CHEMOTHERAPY versus PLACEBO + CHEMOTHERAPY for previously untreated locally recurrent inoperable or metastatic triple negative breast cancer

Patient Population: Triple negative locally recurrent inoperable or metastatic breast cancer

Locations: Toronto, Ottawa, Montreal

Click HERE for more information.


Title of Study: A Phase 2 randomized, double-blinded, controlled study of TUCATINIB versus PLACEBO in combination with CAPECITABINE and TRASTUZUMAB in patients with pretreated unresectable locally advanced or metastatic HER2 positive breast cancer

Patient Population: HER2+ locally advanced or metastatic breast cancer

Locations: Edmonton, Calgary, St. John’s, Halifax, Toronto, Québec, Montreal, Regina, Saskatoon

Click HERE for more information.


Title of Study: A Phase 2 study of ABEMACICLIB in patients with brain metastases secondary to hormone receptor positive breast cancer

Patient Population: HR+ metastatic breast cancer

Locations: Ottawa

Click HERE for more information.


Title of Study: A Phase 3, randomised, double-blind, placebo-controlled study of ATEZOLIZUMAB in combination with PACLITAXEL compared with PLACEBO with PACLITAXEL for patients with previously untreated inoperable locally advanced or metastatic triple negative breast cancer.

Patient Population: locally advanced or metastatic triple negative breast cancer

Locations: Edmonton, Calgary, Kingston, London, Toronto, Montreal, Quebec City, Sherbrooke

Click HERE for more information.

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